The following is an excerpt from Eric Mack | March 23, 2017 | CNET.com |
Researchers have made a breakthrough that could lead to antiaging drugs, help astronauts survive trips to Mars and just make humans more resilient in general. Oh, is that all?
Scientists from Harvard Medical School and the University of New South Wales in Australia have discovered a critical step in the process that allows the cells in our bodies to repair their damaged DNA.
Your cells' DNA takes a beating more often than you might think -- every time you go out in the sun, for instance. Fortunately, cells also have the capability to fix up their DNA, but that ability declines as we age for reasons that aren't yet fully understood.
The team's findings will be published in the Friday issue of the journal Science and outline the previously unknown role a molecule found in all living cells called NAD+ (the oxidized form of Nicotinamide adenine dinucleotide) plays in DNA repair.
When researchers treated young mice and older mice with a NAD+ "booster" called Nicotinamide mononucleotide (NMN) it improved the animals' ability to repair DNA damaged by exposure to radiation or old age.
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